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Yang Sun Selected Research

Oculocerebrorenal Syndrome (Lowe Syndrome)

1/2021OCRL regulates lysosome positioning and mTORC1 activity through SSX2IP-mediated microtubule anchoring.
1/2020Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation.
10/2017Loss of OCRL increases ciliary PI(4,5)P2 in Lowe oculocerebrorenal syndrome.
9/2014Primary cilia signaling mediates intraocular pressure sensation.
1/2013Compensatory Role of Inositol 5-Phosphatase INPP5B to OCRL in Primary Cilia Formation in Oculocerebrorenal Syndrome of Lowe.

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Yang Sun Research Topics

Disease

195Neoplasms (Cancer)
11/2022 - 06/2006
63Inflammation (Inflammations)
04/2022 - 07/2005
42Colitis
01/2022 - 11/2008
37Carcinogenesis
03/2021 - 09/2008
30Neoplasm Metastasis (Metastasis)
12/2021 - 12/2009
29Breast Neoplasms (Breast Cancer)
03/2022 - 02/2012
26Infections
05/2022 - 03/2010
26Body Weight (Weight, Body)
04/2022 - 11/2009
23Colorectal Neoplasms (Colorectal Cancer)
11/2020 - 12/2009
18Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2022 - 11/2009
15Fibrosis (Cirrhosis)
07/2022 - 03/2008
15Colonic Neoplasms (Colon Cancer)
04/2022 - 10/2010
13Alzheimer Disease (Alzheimer's Disease)
01/2022 - 05/2012
13Contact Dermatitis (Eczema, Contact)
05/2017 - 06/2003
12Psoriasis (Pustulosis Palmaris et Plantaris)
04/2022 - 07/2015
12Colitis-Associated Neoplasms
04/2022 - 12/2009
11Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 03/2011
11Melanoma (Melanoma, Malignant)
01/2021 - 12/2009
11Osteosarcoma (Osteogenic Sarcoma)
01/2021 - 09/2017
11Lymphangioleiomyomatosis (Lymphangiomyomatosis)
10/2017 - 07/2013
10Cataract (Cataracts)
08/2022 - 01/2013
10Glaucoma
01/2022 - 01/2013
10Sepsis (Septicemia)
01/2022 - 05/2006
10Myocardial Infarction
01/2022 - 08/2014
10Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2022 - 05/2009
10Ovarian Neoplasms (Ovarian Cancer)
01/2022 - 07/2013
10COVID-19
10/2021 - 01/2020
10Carcinoma (Carcinomatosis)
03/2021 - 06/2010
10Hypoxia (Hypoxemia)
01/2021 - 06/2012
10Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2021 - 06/2007
10Tuberous Sclerosis (Bourneville's Disease)
10/2017 - 07/2013
9Wounds and Injuries (Trauma)
04/2022 - 01/2015
9Lung Neoplasms (Lung Cancer)
02/2022 - 01/2013
9Pain (Aches)
01/2022 - 01/2011
9Heart Failure
01/2022 - 09/2010
9Cardiovascular Diseases (Cardiovascular Disease)
11/2021 - 05/2010
9Acute Lung Injury
01/2021 - 04/2008
9Necrosis
01/2021 - 09/2006
8Pancreatic Neoplasms (Pancreatic Cancer)
11/2022 - 06/2013
8Lung Injury
07/2022 - 04/2008
8Fatigue
06/2022 - 01/2016
8Reperfusion Injury
01/2022 - 08/2014
8Hypersensitivity (Allergy)
07/2021 - 07/2005
8Liver Cirrhosis (Hepatic Cirrhosis)
03/2021 - 03/2008
7Pneumonia (Pneumonitis)
09/2022 - 09/2014
7Insulin Resistance
07/2022 - 06/2002
7Rheumatoid Arthritis
01/2022 - 04/2012
7Mitochondrial Diseases (Mitochondrial Disease)
11/2021 - 04/2015
7Myocardial Ischemia (Ischemic Heart Diseases)
08/2019 - 10/2011

Drug/Important Bio-Agent (IBA)

65Proteins (Proteins, Gene)FDA Link
04/2022 - 03/2010
47Pharmaceutical PreparationsIBA
11/2022 - 06/2003
33CytokinesIBA
03/2022 - 09/2006
31Biomarkers (Surrogate Marker)IBA
06/2022 - 09/2008
20Biological ProductsIBA
03/2022 - 01/2008
19InflammasomesIBA
07/2022 - 05/2013
18Polysaccharides (Glycans)IBA
11/2021 - 11/2008
15MicroRNAs (MicroRNA)IBA
03/2022 - 01/2015
15Cisplatin (Platino)FDA LinkGeneric
02/2022 - 09/2012
15Therapeutic UsesIBA
01/2022 - 11/2009
15andrographolideIBA
01/2022 - 12/2012
15Dextran SulfateIBA
12/2021 - 03/2013
14Messenger RNA (mRNA)IBA
03/2022 - 06/2002
12Interleukin-6 (Interleukin 6)IBA
03/2022 - 09/2009
12Picryl Chloride (Trinitrochlorobenzene)IBA
01/2016 - 06/2003
11Long Noncoding RNAIBA
01/2022 - 01/2018
11Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2021 - 05/2006
11Sulfonic AcidsIBA
04/2021 - 11/2008
11CurcuminIBA
04/2021 - 12/2009
11LipopolysaccharidesIBA
01/2021 - 05/2006
11Reactive Oxygen Species (Oxygen Radicals)IBA
01/2021 - 01/2015
10Capsules (Microcapsules)IBA
08/2022 - 08/2012
10Imiquimod (Aldara)FDA LinkGeneric
04/2022 - 01/2016
10Tyrosine (L-Tyrosine)FDA Link
04/2022 - 10/2012
10RNA (Ribonucleic Acid)IBA
03/2022 - 01/2020
10Doxorubicin (Adriamycin)FDA LinkGeneric
01/2021 - 10/2012
10Mechanistic Target of Rapamycin Complex 1IBA
01/2021 - 01/2014
9Phosphoric Monoester Hydrolases (Phosphatases)IBA
04/2022 - 12/2009
9Glucose (Dextrose)FDA LinkGeneric
04/2022 - 11/2009
9Phosphotransferases (Kinase)IBA
01/2022 - 02/2014
9CateninsIBA
10/2021 - 03/2014
9LigandsIBA
01/2021 - 11/2008
9lipoarabinomannan (LAM)IBA
11/2016 - 07/2013
8Orosomucoid (Seromucoid)IBA
06/2022 - 01/2016
8AntioxidantsIBA
04/2021 - 10/2012
8Beclin-1IBA
11/2020 - 05/2009
8ArsenicIBA
01/2013 - 06/2006
7Interleukin-17 (Interleukin 17)IBA
03/2022 - 03/2012
7DNA (Deoxyribonucleic Acid)IBA
01/2022 - 10/2017
7Indicators and Reagents (Reagents)IBA
01/2022 - 02/2012
7InterferonsIBA
01/2022 - 01/2013
7LipidsIBA
11/2021 - 06/2009
7Insulin (Novolin)FDA Link
01/2021 - 06/2002
7CollagenIBA
11/2020 - 06/2009

Therapy/Procedure

89Therapeutics
06/2022 - 01/2010
23Drug Therapy (Chemotherapy)
02/2022 - 03/2011
19Chinese Traditional Medicine (Traditional Chinese Medicine)
07/2022 - 12/2009
15Immunotherapy
01/2022 - 01/2018
11Radiotherapy
07/2022 - 12/2010
9Lasers (Laser)
08/2022 - 06/2010
9Precision Medicine
10/2021 - 10/2012